Fibromyalgia (FM) is a medical condition characterized by chronic widespread pain and a heightened pain response to pressure. Other symptoms include feeling tired to a degree that normal activities are affected, sleep problems, and troubles with memory. Some people also report restless legs syndrome, bowel or bladder problems, numbness and tingling, and sensitivity to noise, lights or temperature. Fibromyalgia is frequently associated with depression, anxiety, and post-traumatic stress disorder. Other types of chronic pain are also frequently present. (continue reading on Wikipedia)
Fibromyalgia (FM) and LDN
As a disease involving immune dysfunction, FM can respond well to Low Dose Naltrexone. Additionally, chronic pain is the dominant symptom of FM, and LDN is especially effective in relieving chronic pain. Fibromyalgia is one of the most common conditions among LDN patients.
Johnson B1, Ulberg S, Shivale S, Donaldson J, Milczarski B, Faraone SV. , Fibromyalgia, autism, and opioid addiction as natural and induced disorders of the endogenous opioid hormonal system., Discov Med. 2014 Oct;18(99):209-20. https://www.ncbi.nlm.nih.gov/pubmed/19453963
Deshpande S1, Rivera DE1, Younger JW2, Nandola NN3., A control systems engineering approach for adaptive behavioral interventions: illustration with a fibromyalgia intervention., Transl Behav Med. 2014 Sep;4(3):275-89. doi: 10.1007/s13142-014-0282-z. https://www.ncbi.nlm.nih.gov/pubmed/19453963
Younger J1, Noor N, McCue R, Mackey S. , Low-dose naltrexone for the treatment of fibromyalgia: findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels., Arthritis Rheum. 2013 Feb;65(2):529-38. doi: 10.1002/art.37734 https://www.ncbi.nlm.nih.gov/pubmed/19453963
Ramanathan S1, Panksepp J, Johnson B. , Is fibromyalgia an endocrine/endorphin deficit disorder? Is low dose naltrexone a new treatment option?, Psychosomatics. 2012 Nov-Dec;53(6):591-4. doi: 10.1016/j.psym.2011.11.006. Epub 2012 Apr 4. https://www.ncbi.nlm.nih.gov/pubmed/1945396
Younger J1, Mackey S. , Fibromyalgia symptoms are reduced by low-dose naltrexone: a pilot study., Pain Med. 2009 May-Jun;10(4):663-72. doi: 10.1111/j.1526-4637.2009.00613.x. Epub 2009 Apr 22. https://www.ncbi.nlm.nih.gov/pubmed/19453963